the medical applications of nuclear transfer (cloning) and embryonic stem cell technologies
Michael D. West
The transfer of a body cell into the environment of an egg cell can "reprogram" it back to an embryonic developmental state. We have recently demonstrated that such technology actually rebuilds the replicative lifespan as well, suggesting that "young" cells can be derived from "old" cells.
... to be able to offer any patient, even an aged patient, young healthy embryonic stem cells of from which any kind of cell could be made all of which would be their own cells, not expected to be rejected by their immune system.
December 4, 2001
U.S. Senate: http://appropriations.senate.gov/releases/record.cfm?id=179832
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Advanced Cell Technology
is a biotechnology company focused
on discovering and developing the applications of cloning technology in
human medicine, agriculture and veterinary medicine.
The oocyte [egg cell] apparently is the rejuvenating environment that makes babies young. The old cells were not merely returned to a youthful state. Remarkably, they were actually given a longer life span than those from normal animals... telomeres that look like newborn calves despite the fact that they were cloned from senescent cells... "Our results show that cloning actually has the potential to reverse the aging of cells," said Dr. Lanza. "This has profound implications for treating age-related disease and for understanding the actual mechanisms behind the aging process...
The company's scientific objective in applying cloning to human medicine is to create human stem cells -- the basic primitive cells that ultimately form all the cells in the body. These basic building block cells would then be capable of differentiating into a variety of human cells, such as heart cells, neurons, blood cells or islets for transplant therapies. By demonstrating that the cellular clocks of these stem cells can be reset through the cloning process, ACT has shown that human therapeutic cloning may give scientists the potential to grow young cells, tissues, and organs for an aging population
2000 Science Blog: http://www.scienceblog.com/community/older/2000/C/200002545.html
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California Stem Cell Agency
News, information and commentary
on public policy and business issues
involving California's new stem
cell agency, the California Institute for Regenerative Medicine,
created by Prop.
71.
Report: http://californiastemcellreport.blogspot.com/
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The Institute for Regeneration
Medicine |
University of California, San
Francisco
Story: http://www.stemcellfunding.org/news_detail.aspx?id=051106A
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Gail Martin's Lab: http://www.ucsf.edu/grmlab/
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image site
page link |
Scientific Images: http://www.phototakeusa.com/ |
NPR Radio Audio
Stem Cell Ethics | Human Eggs | Fetal Cell | Surprisingly Healthy | new research | federal funding | new source | debate | LeonClass | Bush Veto | California |
Stem Cell Now - some consider the greatest discovery since nuclear fusion |
Stem Cell Research Agency
SAN FRANCISCO - California’s novel, $3 billion stem cell research institute is a legitimate state agency, and two lawsuits challenging its constitutionality have no merit, a state judge ruled Friday.
The decision came a month after a four-day trial in which lawyers with connections to anti-abortion groups claimed the country’s most ambitious stem cell research agency violated California law because it wasn’t a true state agency and its managers had a host of conflicts of interest.
But Alameda County Superior Court Judge Bonnie
Lewman Sabraw handed the California Institute for Regenerative Medicine
an unambiguous victory, writing that the lawsuits failed to show the voter-approved
law that created the agency in 2004 “is clearly, positively and unmistakably
unconstitutional.”
Alliance: http://www.curesforcalifornia.com/
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Advocating for the advancement of breakthrough
research and technologies in regenerative medicine - including stem cell
research and somatic cell nuclear transfer - in order to cure disease and
alleviate suffering for individuals with life-threatening illnesses and
disorders.
Coalition for the Advancement
of Medical Research:
http://www.stemcellfunding.org/
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UCSF Glossary: http://stemcellfacts.ucsf.edu/glossary.php
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